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KMID : 0357920100440040420
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Korean Journal of Pathology
2010 Volume.44 No. 4 p.420 ~ p.425
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Solitary Fibrous Tumor of the Kidney
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Kim Sun-A
Hwang Jeong-Eun
Ro Jae Y.
Cho Kyung-Ja
Song Cheryn
Kim Mi-Jung
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Abstract
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Solitary fibrous tumor (SFT) is a benign mesenchymal neoplasm usually occurring in the pleura. Kidney is one of the rarest sites for SFT. We report here on two cases of renal SFT found in 30-year-old and 33-year-old men with review of the literatures. Both cases manifested as well-enhanced solid masses in kidney and radical nephrectomies were done. The tumors consisted of bland-looking spindle cells arranged in short, ill-defined fascicles and storiform pattern with characteristic hemangiopericytoma-like blood vessels. The tumor cells were strongly positive for CD34 and CD99, focally positive for bcl-2, and negative for cytokeratin and human melanoma black-45 on immunohistochemical stainings. Possibility of SFT should be considered in the differential diagnosis of a renal mass which consists of benign-looking spindle cells and hemangiopericytomatous blood vessels. Immunohistochemical staining for CD34 is essential to confirm the renal solitary fibrous tumor.
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KEYWORD
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Solitary fibrous tumor, Kidney, Immunohistochemistry
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